This, he said in his key note address during the celebration of the International Day for Non-Violence.
Mr Guterres said it is also a timely reminder to strive to uphold values that Mr Gandhi lived by the promotion of dignity, equal protection for all and communities living together in peace.
He highlighted that this year they have a special duty, to stop fighting and focus on the common enemy - COVID-19.
He noted that there is only one winner in conflict during a pandemic, the virus itself.
Mr Guterres said as the pandemic took hold, he called for a global ceasefire, adding that there is need for a new push by the international community to make this a reality by the end of the year.
The cease-fire he said would ease immense suffering, help lower the risk of famine and create space for negotiations towards peace.
He added that deep mistrust stands in the way, yet he sees reasons for hope.
Now, he said is the time to intensify efforts, urging all to be inspired by the spirit of Gandhi and the enduring principles of the UN Charter.